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Chemical Senses 21: 55-58,
© 1996

research-article

Effects of Calmodulin Antisense Oligonucleotides on Chemoresponse in Paramecium

J. Yano, D. Fraga1, R. Hinrichsen2 and J.L. Van Houten

University of Vermont, Department of Biology Burlington, VT 04505, USA 1College of Wooster Wooster, OH 44691, USA 2Hutchinson Cancer Center Seattle, WA 98104, USA

Correspondence to be sent to: J. L. Van Houten, University of Vermont, Department of Biology, Burlington, VT 04505, USA

The calcium/calmodulin-regulated Ca-ATPase of the plasma membrane is implicated in Paramecium chemosensory transduction. Calmodulin antisense oligonucleotides electroporated into Paramecium disrupt chemosensory responses to sodium acetate but not to ammonium chloride. Chem. Senses 21: 55–58, 1996.


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