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Chemical Senses 21: 75-79,
© 1996

other

Loss of Olfactory Function Leads to a Decrease of Trigeminal Sensitivity

T. Hummel, S. Barz, J. Lötsch, S. Roscher, B. Kettenmann and G. Kobal

Department of Experimental and Clinical Pharmacology and Toxicology, University of Erlangen-N{diaeresis}rnberg Krankenhausstr. 9, 91054 Erlangen, Germany

Correspondence to be sent to: Dr Thomas Hummel, Department of Experimental and Clinical Pharmacology and Toxicology Krankenhausstr. 9, 91054 Erlangen, Germany

Healthy controls were compared to patients with decreased olfactory sensitivity (n = 32) to investigate interactions between the olfactory and trigeminal systems. Amplitudes of chemo-somatosensory event-related potentials in response to suprathreshold trigeminal stimuli (CO2) were found to be smaller in patients (P<0.05) indicating a decrease of trigeminally mediated sensations. Chem. Senses 21: 75–79, 1996.


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