Skip Navigation

This Article
Right arrow FREE Full Text (PDF) Freely available
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (16)
Right arrowRequest Permissions
Right arrow Disclaimer
Google Scholar
Right arrow Articles by Halpern, M.
Right arrow Articles by Jia, C.
Right arrow Search for Related Content
PubMed
Right arrow Articles by Halpern, M.
Right arrow Articles by Jia, C.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Chemical Senses 23: 477-481,
© 1998 Oxford University Press

Heterogeneity in the Accessory Olfactory System

Mimi Halpern, Lena Shnayder Shapiro and Changping Jia

Department of Anatomy and Cell Biology and Program in Neural and Behavioral Science, SUNY Health Science Center at Brooklyn Brooklyn, NY 11203, USA

Correspondence to be sent to: Dr Mimi Halpern, Department of Anatomy and Cell Biology, SUNY Health Science Center at Brooklyn, 450 Clarkson Avenue, Brooklyn, NY 11203, USA. e-mail: mhalpern{at}netmail.hscbklyn.edu


  Abstract

The mammalian accessory olfactory bulb (AOB) is chemoarchitecturally heterogeneous in that it stains differentially with a number of markers; the receptor cells that project to the AOB are similarly heterogeneous. What is the significance of this heterogeneity? We have found that the AOB of the gray, short-tailed opossum, Monodelphis domestica, stains differentially with a number of ‘markers’: antibodies to olfactory marker protein (OMP) and the {alpha} subunit of the G protein Gi2, the lectin of Vicia villosa and NADPH-diaphorase. These markers stain the rostral AOB more strongly than the caudal AOB whereas, the G protein subunit Go{alpha} is located predominantly in the posterior subdivision of the AOB. This heterogeneity in the chemoarchitecture of the AOB may reflect a fundamental organizational dichotomy within the vomeronasal system that corresponds to a functional dichotomy. The vomeronasal sensory epithelium also exhibits a chemoarchitectural heterogeneity: receptor cells in the basal third are Go{alpha}-immunoreactive whereas the cells in the middle third are Gi2{alpha}-immunoreactive. Tracing studies using WGA-HRP demonstrate that the neurons in the middle third of the vomeronasal sensory epithelium project their axons to the anterior AOB whereas those in the basal third appear to project to the posterior AOB.

Accepted 18 March 1997


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Chem SensesHome page
I. Salazar, P. S. Quinteiro, M. Lombardero, and J. M. Cifuentes
Histochemical Identification of Carbohydrate Moieties in the Accessory Olfactory Bulb of the Mouse Using a Panel of Lectins
Chem Senses, July 1, 2001; 26(6): 645 - 652.
[Abstract] [Full Text] [PDF]


Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.