Skip Navigation

This Article
Right arrow Full Text Freely available
Right arrow FREE Full Text (PDF) Freely available
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (2)
Right arrowRequest Permissions
Right arrow Disclaimer
Google Scholar
Right arrow Articles by Ishimaru, T.
Right arrow Articles by Furukawa, M.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Ishimaru, T.
Right arrow Articles by Furukawa, M.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Chem. Senses 27: 711-717, 2002
© Oxford University Press 2002

Potential Changes with Gamma-band Oscillation at the Frontal Scalp Elicited by Intravenous Olfactory Stimulation in Humans

Tadashi Ishimaru1, Sachiko Hatanaka2, Tsuyoshi Yata2, Isao Horikawa1, Toshiaki Tsukatani1, Toshiro Nishimura1, Takaki Miwa1,2 and Mitsuru Furukawa1,2

1 Department of Otorhinolaryngology, Head and Neck Surgery, School of Medicine, Kanazawa University, Kanazawa 920-8641, Japan 2 Division of Neuroscience, Clinical Neuroscience, Graduate School of Medicine, Kanazawa University, Kanazawa 920-8641, Japan

Correspondence to be sent to: Tadashi Ishimaru, Department of Otorhinolaryngology, School of Medicine, Kanazawa University, 13-1 Takara-machi, Kanazawa 920-8641, Japan. e-mail: ishimar{at}orl.m.kanazawa-u.ac.jp

Intravenous olfaction is a unique stimulation method often used in Japan to diagnose olfactory disturbances. Odorant is injected into a vein and transported by blood flow and respiration to the upper air tract. The intravenous olfaction might allow the potential at the frontal scalp to be recorded without contamination from electromyograms, such as those caused by sniffing. We injected Alinamin (thiamine propyldisulphide) into healthy subjects according to a standard protocol for clinical intravenous olfaction testing and we simultaneously recorded potential changes at the frontal scalp. When Alinamin was injected into the right median cubital vein over a 20 s period, the potential changes with gamma-band oscillations were detected 17.6 ± 6.7 s (mean ± SD) after the start of the injection. The main frequency component of this gamma-band oscillation is 30-160 Hz. The gamma-band oscillation elicited by intravenous olfactory stimulation (VOP) was similar to the induced wave of the olfactory bulb. Mapping the VOPs on the frontal scalp of a subject with less developed frontal sinuses and the relation between the thickness of the frontal sinuses and VOP amplitude suggest an intracranial source, possibly the olfactory bulb. The gamma-band potential at the frontal scalp is a useful measure of central disturbance.


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Chem SensesHome page
T. Ishimaru, T. Yata, and S. Hatanaka-Ikeno
Hemodynamic Response of the Frontal Cortex Elicited by Intravenous Thiamine Propyldisulphide Administration
Chem Senses, March 1, 2004; 29(3): 247 - 251.
[Abstract] [Full Text] [PDF]


Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.