Skip Navigation


Chemical Senses Advance Access originally published online on May 18, 2005
Chemical Senses 2005 30(5):435-442; doi:10.1093/chemse/bji038
This Article
Right arrow Full Text Freely available
Right arrow FREE Full Text (PDF) Freely available
Right arrow All Versions of this Article:
30/5/435    most recent
bji038v1
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Disclaimer
Google Scholar
Right arrow Articles by de Brito Sanchez, M. G.
Right arrow Articles by Kaissling, K.-E.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by de Brito Sanchez, M. G.
Right arrow Articles by Kaissling, K.-E.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

© The Author 2005. Published by Oxford University Press. All rights reserved. For permissions, please e-mail: journals.permissions@oupjournals.org

Inhibitory and Excitatory Effects of Iodobenzene on the Antennal Benzoic Acid Receptor Cells of the Female Silk Moth Bombyx mori L.

María Gabriela de Brito Sanchez1,2,3 and Karl-Ernst Kaissling2

1 Laboratorio de Fisiología de Insectos, FCEyN, Universidad de Buenos Aires, Ciudad Universitaria, 1428 Buenos Aires, Argentina and 2 Max-Planck-Institut für Verhaltensphysiologie, 82319 Seewiesen/Starnberg, Germany 3 Present address: Centre de Recherches sur la Cognition Animale—UMR 5169, Université Paul-Sabatier—CNRS, 118, route de Narbonne, 31062 Toulouse cedex 04, France

Correspondence to be sent to: Dr Maria Gabriela de Brito Sanchez, Centre de Recherches sur la Cognition Animale—UMR 5169, Université Paul-Sabatier—CNRS, 118, route de Narbonne, 31062 Toulouse cedex 04, France. e-mail: debrito{at}cict.fr

As shown in single-sensillum recordings, iodobenzene has a bimodal effect on the receptor cell tuned to benzoic acid (BA) of the female silk moth Bombyx mori. Exposure to iodobenzene causes an inhibition of the response to BA. With stimulation by iodobenzene alone, a reduction of basic nerve impulse firing during exposure is followed by a transient post-stimulus excitation (rebound). We suggest that inhibition suppresses excitation during exposure but fades afterwards more rapidly than excitation. Due to the spatial equivalence of the iodine and the acid residue, these effects might indicate opposing interactions of iodobenzene with the specific site for the key compound BA. This is supported by the fact that substitutions by smaller halogens are less effective in both inhibition and rebound. The inhibitory effect but not the rebound with iodobenzene alone was also observed in receptor cells tuned to key compounds other than benzoic acid, e.g. in the cell most sensitive to 2,6-dimethyl-5-heptene-2-ol (DMH-cell) occurring in the same sensillum as the BA-cell, or in the bombykol- and bombykal-cells of the male. At least in these cells the inhibitory effect might reflect the action of iodobenzene on a general site, e.g. the lipid matrix of the plasma membrane of the receptor cells.

Key words: aniline, benzoic acid receptor cell, Bombyx mori, inhibition, iodobenzene, olfactory receptor


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?




Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.