Skip Navigation


Chemical Senses Advance Access originally published online on May 10, 2007
Chemical Senses 2007 32(6):569-581; doi:10.1093/chemse/bjm025
This Article
Right arrow Full Text Freely available
Right arrow FREE Full Text (PDF) Freely available
Right arrow All Versions of this Article:
32/6/569    most recent
bjm025v1
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (3)
Right arrowRequest Permissions
Right arrow Disclaimer
Google Scholar
Right arrow Articles by Veldhuizen, M. G.
Right arrow Articles by Small, D. M.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Veldhuizen, M. G.
Right arrow Articles by Small, D. M.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

© The Author 2007. Published by Oxford University Press. All rights reserved. For permissions, please e-mail: journals.permissions@oxfordjournals.org

Trying to Detect Taste in a Tasteless Solution: Modulation of Early Gustatory Cortex by Attention to Taste

Maria G. Veldhuizen1,2, Genevieve Bender1,3, R. Todd Constable3,4 and Dana M. Small1,2,3

1 Affective Sensory Neuroscience, The John B. Pierce Laboratory, 290 Congress Avenue, New Haven, CT 06519, USA 2 Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA 3 Interdepartmental Neuroscience, Yale University School of Medicine, New Haven, CT, USA 4 Department of Radiology, Yale University School of Medicine, New Haven, CT, USA

Correspondence to be sent to: Maria G. Veldhuizen, Affective Sensory Neuroscience, The John B. Pierce Laboratory, 290 Congress Avenue, New Haven, CT 06519, USA. e-mail: mveldhuizen{at}jbpierce.org


  Abstract

Selective attention is thought to be associated with enhanced processing in modality-specific cortex. We used functional magnetic resonance imaging to evaluate brain response during a taste detection task. We demonstrate that trying to detect the presence of taste in a tasteless solution results in enhanced activity in insula and overlying operculum. The same task does not recruit orbitofrontal cortex (OFC). Instead, the OFC responds preferentially during receipt of an unpredicted taste stimulus. These findings demonstrate functional specialization of taste cortex in which the insula and the overlying operculum are recruited during taste detection and selective attention to taste, and the OFC is recruited during receipt of an unpredicted taste stimulus.

Key words: baseline shift, fMRI, gustatory cortex, humans, insula

Accepted 27 March 2007


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Cereb CortexHome page
F. Grabenhorst, E. T. Rolls, and A. Bilderbeck
How Cognition Modulates Affective Responses to Taste and Flavor: Top-down Influences on the Orbitofrontal and Pregenual Cingulate Cortices
Cereb Cortex, July 1, 2008; 18(7): 1549 - 1559.
[Abstract] [Full Text] [PDF]


Disclaimer:
Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.