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Chemical Senses 2005 30(Supplement 1):i23-i24; doi:10.1093/chemse/bjh094
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Chemical Senses Vol. 30 No. suppl 1 © Oxford University Press 2005; all rights reserved

Regional Expression Patterns of T1r Family in the Mouse Tongue

Yuko Kusakabe1,2, Mi-Ryung Kim1, Hirohito Miura1,2, Yoichiro Shindo3, Yuzo Ninomiya2,4 and Akihiro Hino1,2

1 National Food Research Institute, 2 Bio-oriented Technology Research Advancement Institution, 3 Asahi Breweries Ltd and 4 Kyushu University

Correspondence to be sent to: Yuko Kusakabe, e-mail: ykusa@nfri.affrc.go.jp

Key words: taste receptor, circumvallate papillae, fungiform papillae, umami, sweet, gustducin

The first 10% of the full text of this article appears below.


   Introduction
 
The T1r family is one of the receptor family belong to class C type of G protein coupled receptors, and comprised of three taste bud-specific receptors, T1r1, T1r2 and T1r3 (Nelson et al., 2001Go). T1r1 and T1r2 are known to have distinctive patterns of regional expression, respectively (Hoon et al., 1999Go). T1r1 is expressed in taste buds in the fungiform papillae, but is rare in the taste buds of circumvallate papillae. In contrast, T1r2 is rarely expressed in fungiform papillae but is expressed in all taste buds of the circumvallate papillae. T1r3 is strongly expressed in both fungiform and circumvallate papillae (Kitagawa et al., 2001Go; Nelson et al., 2001Go) and forms an amino-acid (umami) receptor and . . . [Full Text of this Article]


   Results and discussion
 
Comparison of T1rs expression in circumvallate and fungiform papillae

Expression patterns of T1rs with gustducin in circumvallate papillae and fungiform papillae


   Acknowledgements
 

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