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Chem. Senses 26: 91-93, 2001
© Oxford University Press 2001

Clinical Bitterness Masking Test for Phantogeusia

Tadashi Ishimaru, Sachiko Hatanaka, Takaki Miwa and Mitsuru Furukawa

Department of Otorhinolaryngology, School of Medicine, Kanazawa University, 13-1 Takara-machi, Kanazawa 920-8641, Japan

Correspondence to be sent to: Tadashi Ishimaru, Department of Otorhinolaryngology, School of Medicine, Kanazawa University, 13-1 Takara-machi, Kanazawa 920-8641, Japan. e-mail: ishimar{at}orl.m.kanazawa-u.ac.jp

It is difficult to determine the reason why a patient complains of a bitter taste when their mouth is empty. We examined a new diagnostic test using a bitterness masking substance. The bitterness masking substance, ‘Benecoat BMI-60’ (hereafter BMI-60), is a masking substance specific to the taste cells’ bitterness receptors. After patients gargled with BMI-60 solutions, the phantom sensation of bitterness was masked in some patients, but was not masked in others. Bitter substances in saliva seemed to be masked by BMI-60, but bitterness did not seem to be masked when the locus of the phantom sensation was within the peripheral nerve and/or the brain. The bitterness masking test is useful for diagnosis of the phantom sensation of bitter taste.


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