Chem. Senses 27: 289-291,
2002
© Oxford University Press 2002
SYMPOSIUM: Proceedings of a Symposium on Functional Genomics in Neural Systems |
High-throughput Expression Profiling Techniques
Department of Physiology, University of Kentucky, Lexington, KY 40536-0298, USA
Correspondence to be sent to: Timothy S. McClintock, Department of Physiology, University of Kentucky, 800 Rose St, Lexington, KY 40536-0298, USA. e-mail: mcclint@uky.edu
Great optimism exists that correlating genomics with function will lead to
a better understanding of the detailed workings of the nervous system. The
nearly complete sequencing of the genomes of several eukaryotic species and
the invention of high-throughput expression profiling techniques now provide
the means to rapidly investigate the molecular underpinnings of phenotypic
change with reasonable accuracy. This approach is beginning to have an impact
in neurobiology and we can expect it to be similarly useful for investigating
problems in the chemical senses. Careful thought is necessary, however, in
selecting and matching specific techniques and tissues, in confirming
differences in mRNA abundance and in interpreting the results. A symposium on
Functional Genomics in Neural Systems was held during the AChemS
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