Chemical Senses 4: 215-229,
© 1979
research-article |
A metric for the breadth of tuning of gustatory neurons
Department of Psychology, University of Wyoming Laramie, Wyoming 82071, USA
The breadth of the responsiveness of gustatory neurons to the four basic taste stimuli (sucrose,NaCl, HCl and quinine hydrochloride) is a question of importance to current theories of gustatory quality coding. The mathematical expression of entropy from information theory can provide a measure of the breadth of tuning of these neurons. The entropy measure, as applied here, varies continuously from 0.0 for a unit that responds exclusively to one stimulus (i.e., narrowly tuned) to 1.0 for a cell that responds equivalently to all four of the basic compounds (i.e., broadly tuned). Subtle variations in the neural response profile of a cell, such as those produced by changes in stimulus concentration, are reflected in this measure. Thus, the use of the equation for entropy to describe the responsiveness of gustatory neurons provides a quantitative measure of their breadth of tuning that can be meaningfully applied to the problems of gustatory quality coding.
CiteULike 
Connotea 
Del.icio.us What's this?
This article has been cited by other articles:
|
|
 |
|
  R. Yoshida, A. Miyauchi, T. Yasuo, M. Jyotaki, Y. Murata, K. Yasumatsu, N. Shigemura, Y. Yanagawa, K. Obata, H. Ueno, et al. Discrimination of taste qualities among mouse fungiform taste bud cells J. Physiol., September 15, 2009; 587(18): 4425 - 4439. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 P. M. Di Lorenzo, J.-Y. Chen, and J. D. Victor Quality Time: Representation of a Multidimensional Sensory Domain through Temporal Coding J. Neurosci., July 22, 2009; 29(29): 9227 - 9238. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 C. H. Lemon and R. F. Margolskee Contribution of the T1r3 Taste Receptor to the Response Properties of Central Gustatory Neurons J Neurophysiol, May 1, 2009; 101(5): 2459 - 2471. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P. Kovacs and A. Hajnal Altered Pontine Taste Processing in a Rat Model of Obesity J Neurophysiol, October 1, 2008; 100(4): 2145 - 2157. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
Y. K. Cho and C.-S. Li Gustatory Neural Circuitry in the Hamster Brain Stem J Neurophysiol, August 1, 2008; 100(2): 1007 - 1019. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J.-Y. Chen and P. M. Di Lorenzo Responses to Binary Taste Mixtures in the Nucleus of the Solitary Tract: Neural Coding With Firing Rate J Neurophysiol, May 1, 2008; 99(5): 2144 - 2157. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 L. Mao, Y. K. Cho, and C.-S. Li Modulation of activity of gustatory neurons in the hamster parabrachial nuclei by electrical stimulation of the ventroposteromedial nucleus of the thalamus Am J Physiol Regulatory Integrative Comp Physiol, May 1, 2008; 294(5): R1461 - R1473. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C.-S. Li, L. Mao, and Y. K. Cho Taste-responsive neurons in the nucleus of the solitary tract receive gustatory information from both sides of the tongue in the hamster Am J Physiol Regulatory Integrative Comp Physiol, February 1, 2008; 294(2): R372 - R381. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. M. Breza, K. S. Curtis, and R. J. Contreras Monosodium Glutamate but not Linoleic Acid Differentially Activates Gustatory Neurons in the Rat Geniculate Ganglion Chem Senses, November 1, 2007; 32(9): 833 - 846. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. M. Tomchik, S. Berg, J. W. Kim, N. Chaudhari, and S. D. Roper Breadth of Tuning and Taste Coding in Mammalian Taste Buds J. Neurosci., October 3, 2007; 27(40): 10840 - 10848. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P. M. D. Lorenzo and J. D. Victor Neural Coding Mechanisms for Flow Rate in Taste-Responsive Cells in the Nucleus of the Solitary Tract of the Rat J Neurophysiol, February 1, 2007; 97(2): 1857 - 1861. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. A. McCaughey Taste-Evoked Responses to Sweeteners in the Nucleus of the Solitary Tract Differ between C57BL/6ByJ and 129P3/J Mice J. Neurosci., January 3, 2007; 27(1): 35 - 45. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. Yoshida, N. Shigemura, K. Sanematsu, K. Yasumatsu, S. Ishizuka, and Y. Ninomiya Taste Responsiveness of Fungiform Taste Cells With Action Potentials J Neurophysiol, December 1, 2006; 96(6): 3088 - 3095. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
L. C. Geran and S. P. Travers Single Neurons in the Nucleus of the Solitary Tract Respond Selectively to Bitter Taste Stimuli J Neurophysiol, November 1, 2006; 96(5): 2513 - 2527. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. Kadohisa and D. A. Wilson From the Cover: Separate encoding of identity and similarity of complex familiar odors in piriform cortex PNAS, October 10, 2006; 103(41): 15206 - 15211. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C.-S. Li and Y. K. Cho Efferent projection from the bed nucleus of the stria terminalis suppresses activity of taste-responsive neurons in the hamster parabrachial nuclei. Am J Physiol Regulatory Integrative Comp Physiol, October 1, 2006; 291(4): R914 - R926. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. R. Stapleton, M. L. Lavine, R. L. Wolpert, M. A. L. Nicolelis, and S. A. Simon Rapid Taste Responses in the Gustatory Cortex during Licking J. Neurosci., April 12, 2006; 26(15): 4126 - 4138. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. M. Breza, K. S. Curtis, and R. J. Contreras Temperature Modulates Taste Responsiveness and Stimulates Gustatory Neurons in the Rat Geniculate Ganglion J Neurophysiol, February 1, 2006; 95(2): 674 - 685. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. H. Lemon and D. V. Smith Neural Representation of Bitter Taste in the Nucleus of the Solitary Tract J Neurophysiol, December 1, 2005; 94(6): 3719 - 3729. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Labra, J. H. Brann, and D. A. Fadool Heterogeneity of Voltage- and Chemosignal-Activated Response Profiles in Vomeronasal Sensory Neurons J Neurophysiol, October 1, 2005; 94(4): 2535 - 2548. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. C. Spector and S. P. Travers The representation of taste quality in the Mammalian nervous system. Behav Cogn Neurosci Rev, September 1, 2005; 4(3): 143 - 191. [Abstract] [PDF]
|
|
|
|
|
|
T. C. Pritchard, E. M. Edwards, C. A. Smith, K. G. Hilgert, A. M. Gavlick, T. D. Maryniak, G. J. Schwartz, and T. R. Scott Gustatory Neural Responses in the Medial Orbitofrontal Cortex of the Old World Monkey J. Neurosci., June 29, 2005; 25(26): 6047 - 6056. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Kadohisa, E. T. Rolls, and J. V. Verhagen Neuronal Representations of Stimuli in the Mouth: The Primate Insular Taste Cortex, Orbitofrontal Cortex and Amygdala Chem Senses, June 1, 2005; 30(5): 401 - 419. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. I. Sollars and D. L. Hill In vivo recordings from rat geniculate ganglia: taste response properties of individual greater superficial petrosal and chorda tympani neurones J. Physiol., May 1, 2005; 564(3): 877 - 893. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. V. Verhagen, B. K. Giza, and T. R. Scott Effect of Amiloride on Gustatory Responses in the Ventroposteromedial Nucleus of the Thalamus in Rats J Neurophysiol, January 1, 2005; 93(1): 157 - 166. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
Y. K. Cho, M. E. Smith, and R. Norgren Low-dose furosemide modulates taste responses in the nucleus of the solitary tract of the rat Am J Physiol Regulatory Integrative Comp Physiol, October 1, 2004; 287(4): R706 - R714. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. V. Verhagen, M. Kadohisa, and E. T. Rolls Primate Insular/Opercular Taste Cortex: Neuronal Representations of the Viscosity, Fat Texture, Grittiness, Temperature, and Taste of Foods J Neurophysiol, September 1, 2004; 92(3): 1685 - 1699. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. F. Lundy Jr. and R. Norgren Activity in the Hypothalamus, Amygdala, and Cortex Generates Bilateral and Convergent Modulation of Pontine Gustatory Neurons J Neurophysiol, March 1, 2004; 91(3): 1143 - 1157. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
E. T. Rolls, J. V. Verhagen, and M. Kadohisa Representations of the Texture of Food in the Primate Orbitofrontal Cortex: Neurons Responding to Viscosity, Grittiness, and Capsaicin J Neurophysiol, December 1, 2003; 90(6): 3711 - 3724. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P. M. Di Lorenzo and J. D. Victor Taste Response Variability and Temporal Coding in the Nucleus of the Solitary Tract of the Rat J Neurophysiol, September 1, 2003; 90(3): 1418 - 1431. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. V. Verhagen, E. T. Rolls, and M. Kadohisa Neurons in the Primate Orbitofrontal Cortex Respond to Fat Texture Independently of Viscosity J Neurophysiol, September 1, 2003; 90(3): 1514 - 1525. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. Tamura and R. Norgren Intracranial renin alters gustatory neural responses in the nucleus of the solitary tract of rats Am J Physiol Regulatory Integrative Comp Physiol, April 1, 2003; 284(4): R1108 - R1118. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. T. Simons, Y. Boucher, and E. Carstens Suppression of Central Taste Transmission by Oral Capsaicin J. Neurosci., February 1, 2003; 23(3): 978 - 985. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. V. Verhagen, B. K. Giza, and T. R. Scott Responses to Taste Stimulation in the Ventroposteromedial Nucleus of the Thalamus in Rats J Neurophysiol, January 1, 2003; 89(1): 265 - 275. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 D. A. Fadool, M. Wachowiak, and J. H. Brann Patch-clamp analysis of voltage-activated and chemically activated currents in the vomeronasal organ of Sternotherus odoratus (stinkpot/musk turtle) J. Exp. Biol., March 14, 2002; 204(24): 4199 - 4212. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
Y. K. Cho, C.-S. Li, and D. V. Smith Gustatory Projections from the Nucleus of the Solitary Tract to the Parabrachial Nuclei in the Hamster Chem Senses, January 1, 2002; 27(1): 81 - 90. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. A. McCaughey and M. G. Tordoff Calcium deprivation alters gustatory-evoked activity in the rat nucleus of the solitary tract Am J Physiol Regulatory Integrative Comp Physiol, September 1, 2001; 281(3): R971 - R978. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. A. Gilbertson, J. D. Boughter Jr, H. Zhang, and D. V. Smith Distribution of Gustatory Sensitivities in Rat Taste Cells: Whole-Cell Responses to Apical Chemical Stimulation J. Neurosci., July 1, 2001; 21(13): 4931 - 4941. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. F. Lundy Jr. and R. Norgren Pontine Gustatory Activity Is Altered by Electrical Stimulation in the Central Nucleus of the Amygdala J Neurophysiol, February 1, 2001; 85(2): 770 - 783. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. A. McCaughey and T. R. Scott Rapid induction of sodium appetite modifies taste-evoked activity in the rat nucleus of the solitary tract Am J Physiol Regulatory Integrative Comp Physiol, September 1, 2000; 279(3): R1121 - R1131. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. J. St. John and D. V. Smith Neural Representation of Salts in the Rat Solitary Nucleus: Brain Stem Correlates of Taste Discrimination J Neurophysiol, August 1, 2000; 84(2): 628 - 638. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. F. Lundy Jr. and R. J. Contreras Gustatory Neuron Types in Rat Geniculate Ganglion J Neurophysiol, December 1, 1999; 82(6): 2970 - 2988. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Hajnal, K. Takenouchi, and R. Norgren Effect of Intraduodenal Lipid on Parabrachial Gustatory Coding in Awake Rats J. Neurosci., August 15, 1999; 19(16): 7182 - 7190. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. A. Barry Recovery of Functional Response in the Nucleus of the Solitary Tract After Peripheral Gustatory Nerve Crush and Regeneration J Neurophysiol, July 1, 1999; 82(1): 237 - 247. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. R. Scott, B. K. Giza, and J. Yan Gustatory Neural Coding in the Cortex of the Alert Cynomolgus Macaque: The Quality of Bitterness J Neurophysiol, January 1, 1999; 81(1): 60 - 71. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. Nishijo, T. Uwano, R. Tamura, and T. Ono Gustatory and Multimodal Neuronal Responses in the Amygdala During Licking and Discrimination of Sensory Stimuli in Awake Rats J Neurophysiol, January 1, 1998; 79(1): 21 - 36. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. Nishijo and R. Norgren Parabrachial Neural Coding of Taste Stimuli in Awake Rats J Neurophysiol, November 1, 1997; 78(5): 2254 - 2268. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
B. K. Giza, K. Ackroff, S. A. McCaughey, A. Sclafani, and T. R. Scott Preference conditioning alters taste responses in the nucleus of the solitary tract of the rat Am J Physiol Regulatory Integrative Comp Physiol, October 1, 1997; 273(4): R1230 - R1240. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. Tamura and R. Norgren Repeated sodium depletion affects gustatory neural responses in the nucleus of the solitary tract of rats Am J Physiol Regulatory Integrative Comp Physiol, October 1, 1997; 273(4): R1381 - R1391. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. Kobayashi, H. Nishijo, M. Fukuda, J. Bures, and T. Ono Task-Dependent Representations in Rat Hippocampal Place Neurons J Neurophysiol, August 1, 1997; 78(2): 597 - 613. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. B. Halsell and S. P. Travers Anterior and Posterior Oral Cavity Responsive Neurons Are Differentially Distributed Among Parabrachial Subnuclei in Rat J Neurophysiol, August 1, 1997; 78(2): 920 - 938. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C.-S. Li and D. V. Smith Glutamate Receptor Antagonists Block Gustatory Afferent Input to the Nucleus of the Solitary Tract J Neurophysiol, March 1, 1997; 77(3): 1514 - 1525. [Abstract] [Full Text] [PDF]
|
|